About CBD Oil or Cannabis Flowers and Depression

Cannabidiol (CBD) in the form of CBD Oil and Cannabis flowers to treat Depression. Depression is a term that is often loosely used to describe feeling sad and low. However, major depressive disorder is a much more complicated medical condition. It is a serious mental health disease. Depressive disorder refers to a clinical diagnosis, which is determined by a specific group of symptoms. It allows us to distinguish between the sadness we all feel at times and proper clinical depression. If this applies, a full-spectrum CBD oil and/or CBD-rich Cannabis flowers may be your remedy.

To be diagnosed with a depressive disorder, according to the DSM-5, at least 5 symptoms need to present every day for at least 2 weeks and must cause clinically significant distress or impairment in social, occupational, or other important areas of functioning. 

Depression & legal Cannabis CBD Oil or Flowers to Treat this serious mental disorder
Depression & CBD Oil or Flowers to Treat this serious mental disorder

Symptoms of Serious Clinical Depression Include

  • Depressed mood most of the day, nearly every day.

  • Markedly diminished interest or pleasure in all, or almost all, activities most of the day, nearly every day.

  • Significant weight loss when not dieting or weight gain, or decrease or increase in appetite nearly every day.

  • A slowing down of thought and a reduction of physical movement (observable by others, not merely subjective feelings of restlessness or being slowed down).

  • Fatigue or loss of energy nearly every day.

  • Feelings of worthlessness or excessive or inappropriate guilt nearly every day.

  • Diminished ability to think or concentrate, or indecisiveness, nearly every day.

  • Recurrent thoughts of death, recurrent suicidal ideation without a specific plan, or a suicide attempt or a specific plan for committing suicide.

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How CBD Oil or Cannabis Flowers Work and Help with Depression

In the “serotonin hypothesis” of clinical depression, researchers think that a deficit in serotonin activity is a cause of depression. That is why antidepressants such as Selective Serotonin Reuptake Inhibitors (SSRIs) target serotonin receptors. This is in an attempt to increase serotonin levels in the brain. Despite causing fewer side-effects than previous types of antidepressants, SSRIs still come with a baggage of unwanted and adverse effects. This includes an increased risk of suicide.

The cannabis plant (broad-spectrum CBD Oil and Cannabis Flowers) have shown positive effects on treating anxiety and depression. Please note that none of the research is currently supported by full clinical trials, whether in the United States or any other country.

Scientists Hypothesize that the Benefits of CBD OIl and/or Cannabis Flowers in Cases of Depression are Due to

1. How it affects serotonin levels

One particular study showed that CBD moderates activation of the 5-HT1A receptors involved in brain development and mood, showing antidepressant effects that are comparable to the well-known antidepressant Imipramine. Furthermore, in a 2016 mouse study, researchers found that serotonin and glutamate levels significantly increased after dosing with CBD.

2. How CBD interacts with the Endocannabinoid System

In a 2011 study, researchers investigated the role of the endocannabinoid system (ECS) in depression and found that a deficiency in endocannabinoids can lead to pre-clinical depression. They also found that CBD restores endocannabinoid signaling similar to conventional antidepressant treatments.

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Recommended CBD Product Types and Dosage Against Depression

Our product Types

It’s important to use a high-quality product and do so regularly when using CBD for a condition such as depression.

Sublingual Treatments & Ingestibles

For daily prevention and maintenance, we recommend using a full-spectrum or broad-spectrum potent CBD oil (15% and more), CBD tincture, or CBD capsules. This will allow for a slow onset of action that lasts throughout the day.

Vaping & Smoking

For acute flare-up of depression, vaping CBD or smoking CBD Cannabis flowers can provide almost immediate relief due to its fast onset of action.

CBD Dosage

There are currently no studies exploring CBD dosage for depression in humans. In laboratories, effective antidepressant effects for CBD were found at dosages from 7 mg to 30 mg/kg on rats but extrapolated to humans, this might translate into too high a dose. For cases of depression and given the severity of the ailment, we would rather recommend higher than lower doses and would start with 35-50mg of CBD taken twice daily. If the symptoms are not alleviated with this dosage after 3-4 weeks, increase the daily intake by about 35mg.

35-50mg CBD 2x/day

To help you figure out the right dose for you, head over to our page CBD usage and dosage page.

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