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How Can CBD Help against Epilepsy and Epileptic Attacks?

Cannabidiol (CBD), Epilepsy, and Epileptic Attacks are nowadays often mentioned in the same sentence. It looks like Cannabidiol helps in eliminating Epileptic attacks in people. The U.S. Food and Drug Administration (FDA) just approved Epidiolex. A medication based on CBD, and an oral solution for the treatment of seizures associated with Epilepsy and epileptic attacks. In particular, two rare and severe forms of Epilepsy, Lennox-Gastaut syndrome, and Dravet syndrome. The approval is for patients of two years of age and older.  About 4% of people develop Epilepsy during their lifetime. 

This makes it the fourth most common neurological disorder on the planet. Epilepsy is a disorder of the central nervous system’s spectrum. This is characterized by seizures or periods of unusual behavior, sensations, and sometimes, also a complete loss of awareness. 

Treatment of Epilepsy typically focuses on seizure control with medication. 

Seizures that are often symptomatic of Epilepsy are thought to be caused by abnormal brain activity. Brain activity, similar to a kind of electrical storm. In this instance,neurons begin firing in an abnormal, excessive, and synchronized way. However, there are different types of seizures and forms of epilepsies impacting both children and adults.

CBD against Epilepsy and Epileptic Attack
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Common Symptoms of Epilepsy Include

  • Temporary confusion

  • A staring spell

  • Uncontrollable jerking movements of arms and legs

  • Loss of consciousness or awareness

  • Psychic symptoms such as fear, anxiety or Deja-vu 

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How CBD Works for Epilepsy?

Scientists aren’t exactly sure how CBD helps to reduce seizures. Although they think CBD exerts a complex and cumulative effect on a number of physiological systems. They modulate the brain’s overall neural activity and excitability. Scientists hypothesize that the anti-convulsant effects of CBD are potentially due to: 

1. Its ability to inhibit neural activity

CBD is thought to inhibit neuronal activity via GABA receptors. Those are ionotropic receptors responsible for brain activity and excitability.

2. Its ability to modulate intracellular calcium

Cannabidiol also seems to reduce seizure activity by modulating intracellular calcium, as well as reducing neuronal excitability and neuronal transmission. Scientists hypothesize that CBD does this through interactions with targets such as TRP channels. But also, Gcoupled protein receptor protein 55 (GPR55), and/or voltagedependent anionselective channel protein 1 (VDAC1).

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Recommended CBD Product Types and Dosage for Epilepsy Treatments

Our product Types

It’s important to use high-quality CBD products and do so regularly for people with Epilepsy. There are a few options available:

Epidiolex

EPIDIOLEX® is a Cannabidiol based drug indicated for the treatment of seizure. Especially those associated with Lennox-Gastaut Syndrome (LGS) and Dravet Syndrome (DS). Epidiolex is the first FDA-approved prescription Cannabidiol (CBD) product. It was developed by GW Pharmaceuticals, a healthcare company based in the UK. Epidiolex is only available with a prescription of your doctor and in pharmacies.

Sublingual Treatments & Ingestibles

For daily prevention and maintenance, we recommend using a full-spectrum or broad-spectrum CBD oil However, you may also use a CBD tincture, or a gel cap. This will allow for a slow onset of action that lasts throughout the day.

Vaping & Smoking

For acute flare-up of symptoms, vaping CBD or smoking CBD rich flowers can provide almost immediate relief due to its fast onset of action.

CBD Dosage

The use of CBD for Epilepsy is very personal and dependent on the body’s weight, as well as the type and severity of symptoms. Scientists found effective results for seizure control at 20 and 30 mg of CBD per kg of body weight per day. This is considered a very high-dose and therefore it will translate into high costs. This is, if you intend to use over-the-counter CBD oil or CBD products for Epilepsy.

20-30 mg of CBD / kg of body weight per day

To help you figure out the right dose for you, head over to our CBD usage and dosage page.

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